[Comparison of quality of life in patients living with HIV infection through pharmaceutical care according to CMO methodology vs. conventional follow-up. MAS-VIH project]. / Comparación de la calidad de vida en personas que viven con infección por VIH en seguimiento mediante atención farmacéutica según metodología capacidad motivación-oportunidad vs. seguimiento convencional. Proyecto MAS-VIH.

OBJECTIVE: To compare quality of life, in patients living with HIV infection with pharmaceutical care according to the CMO methodology: capacity, motivation and opportunity versus conventional follow-up. METHODS: Longitudinal, prospective, multicenter, health intervention study, conducted between October 2019 and November 2021 in 14 centers throughout Spain. Patients over 18 years of age, receiving antiretroviral treatment and attending the consultations of the participating Pharmacy Services for 1 year were included. Patients who did not have the autonomy to complete the planned questionnaires were excluded. At baseline, participating centers were randomized to continue using the same systematics of work (traditional follow-up) or to implement the CMO model using patient stratification models, goal setting in relation to pharmacotherapy, use of motivational interviewing, as well as longitudinal follow-up enabled by new technologies. The main variable was the difference in the number of dimensions positively affected in each follow-up arm at 24 weeks of follow-up according to the MOS-HIV questionnaire. In the CMO group, the interventions performed the most frequently were recorded. RESULTS: 151 patients were included. The median age was 51.35 years. A significant improvement in quality of life was found at the end of follow-up in the CMO group, reducing the number of patients with negatively affected dimensions (2/11 vs 8/11). The most frequent interventions carried out in the CMO group, according to the taxonomy, were Motivation (51,7%) and review and validation (49,4%). CONCLUSIONS: The quality of life of patients is higher in those centers that develop Pharmaceutical Care based on the CMO methodology compared to traditional follow-up.

[Analysis of pharmaceutical intervention in outpatients pharmacy department]. / Análisis de las intervenciones farmacéuticas realizadas en el área de pacientes externos.

PURPOSE: To analize the pharmaceutical interventions made in outpatients pharmacy department of a secondary hospital. METHODS: Retrospective and observational study of pharmaceutical interventions made from October 1st 2010 to December 31st 2011. RECORDED DATA: Number of patients, age at the end of the study, diagnostic, prescribing departments, drug-related problems (DRP), negative outcomes associated with medication (NOM), type of pharmaceutical interventions. RESULTS: 231 DRP were found and a pharmaceutical intervention was performed for each DRP in 184 different patients. The main DRPs detected were: drugs interactions (26%), prescription mistakes (15, 6%) and non-compliance (15, 6%). Only 26 (11,2%) DRP caused a NOM. Most interventions were: recommendating treatment changes (35,6%), promoting the monitorization of the effectiveness of treatment (34,6%) and increasing adherence (15,6%). CONCLUSION: The pharmacist activity allows individualized monitoring and is crucial to avoid NOM.

Objetivo: Analizar las intervenciones farmacéuticas realizadas en el Área de Pacientes Externos de un hospital de segundo nivel. Métodos: Estudio observacional, retrospectivo y descriptivo. La recogida de datos se realizó desde octubre de 2010 hasta diciembre de 2011. Variables analizadas: Número de pacientes, edad, Servicio Clínico prescriptor, patología, problemas relacionados con la medicación (PRMs) y resultados negativos asociados a la medicación (RNM), tipo de intervención farmacéutica y principios activos implicados. Resultados principales: Se realizaron 231 intervenciones farmacéuticas, correspondientes a 231 PRMs detectados en 184 pacientes. Principales PRMs detectados: Interacciones farmacológicas (26%), errores en prescripción (15,6%) e incumplimiento terapéutico (15,6%). Sólo 26 (11,2%) PRMs provocaron RNMs. Las intervenciones principales fueron: recomendar modificaciones en el tratamiento (35,6%), potenciar monitorización de la eficacia del tratamiento (34,6%) y potenciar adherencia a los tratamientos (15,6%). Conclusión: La presencia de un farmacéutico optimiza la farmacoterapia de los pacientes evitando que se produzcan elevado número de RNMs.

Análisis de las intervenciones farmacéuticas realizadas en el área de pacientes externos / Analysis of pharmaceutical intervention in outpatients pharmacy department

Objetivo: Analizar las intervenciones farmacéuticas realizadas en el Área de Pacientes Externos de un hospital de segundo nivel. Métodos: Estudio observacional, retrospectivo y descriptivo. La recogida de datos se realizó desde octubre de 2010 hasta diciembre de 2011. Variables analizadas: Número de pacientes, edad, Servicio Clínico prescriptor, patología, problemas relacionados con la medicación (PRMs) y resultados negativos asociados a la medicación (RNM), tipo de intervención farmacéutica y principios activos implicados. Resultados principales: Se realizaron 231 intervenciones farmacéuticas, correspondientes a 231 PRMs detectados en 184 pacientes. Principales PRMs detectados: Interacciones farmacológicas (26%), errores en prescripción (15,6%) e incumplimiento terapéutico (15,6%). Sólo 26 (11,2%) PRMs provocaron RNMs. Las intervenciones principales fueron: recomendar modificaciones en el tratamiento (35,6%), potenciar monitorización de la eficacia del tratamiento (34,6%) y potenciar adherencia a los tratamientos (15,6%). Conclusión: La presencia de un farmacéutico optimiza la farmacoterapia de los pacientes evitando que se produzcan elevado número de RNMs (AU)

Purpose: To analize the pharmaceutical interventions made in outpatients pharmacy department of a secondary hospital. Methods: Retrospective and observational study of pharmaceutical interventions made from October 1st 2010 to December 31st 2011. Recorded data: Number of patients, age at the end of the study, diagnostic, prescribing departments, drug-related problems (DRP), negative outcomes associated with medication (NOM), type of pharmaceutical interventions. Results: 231 DRP were found and a pharmaceutical intervention was performed for each DRP in 184 different patients. The main DRPs detected were: drugs interactions (26%), prescription mistakes (15,6%) and non-compliance (15,6%). Only 26 (11,2%) DRP caused a NOM. Most interventions were: recommendating treatment changes (35,6%), promoting the monitorization of the effectiveness of treatment (34,6%) and increasing adherence (15,6%). Conclusion: The pharmacist activity allows individualized monitoring and is crucial to avoid NOM (AU)